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制药企业的支付与医生在 Medicare Part D 中的处方行为

Drug firms’ payments and physicians’ prescribing behavior in Medicare Part D
Journal of Public Economics · 2021 · Colleen Carey、Ethan M.J. Lieber、Sarah Miller

中文摘要

在一种普遍但有争议的做法中,制药企业在推广处方药的过程中经常向医生提供金钱或实物支付。我们使用一个涵盖 2013 至 2015 年间此类支付全貌的联邦数据库,并将其与 Medicare Part D 中的处方行为相关联。我们通过为每个医生—药品组合设置固定效应来控制支付的定向选择。在一项事件研究中,我们表明医生在接受支付后的数月内会增加对其获得支付的药品的处方量,且没有证据显示在接受支付之前,获得支付与未获得支付的医生之间存在差异化趋势。接下来,我们考察了五个主要药品专利到期的案例研究。从经历专利到期的企业获得支付的医生,其患者转向仿制药的速度与未获得此类支付的医生一样快。此外,利用手工收集的关于三个主要治疗类别的疗效数据,我们表明药品质量在很大程度上不受获得支付的影响。

Abstract

In a pervasive but controversial practice, drug firms frequently make monetary or in-kind payments to physicians in the course of promoting prescription drugs. We use a federal database on the universe of such payments between 2013 and 2015 linked to prescribing behavior in Medicare Part D. We account for the targeting of payments with fixed effects for each physician-drug combination. In an event study, we show that physicians increase prescribing of drugs for which they receive payments in the months just after payment receipt, with no evidence of differential trends between paid and unpaid physicians prior to the payment. Next, we examine five case studies of major drugs going off patent. Physicians receiving payments from the firms experiencing the patent expiry transition their patients just as quickly to generics as physicians who do not receive such payments. In addition, using hand-collected efficacy data on three major therapeutic classes, we show that drug quality is largely unaffected by the receipt of payments.
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