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我们能从检测和住院数据中了解到SARS-CoV-2流行率的哪些信息?

What Can We Learn about SARS-CoV-2 Prevalence from Testing and Hospital Data?
Review of Economics and Statistics · 2024 · Daniel W. Sacks、Nir Menachemi、Peter J. Embí、Coady Wing

中文摘要

衡量一般人群中活跃SARS-CoV-2感染的流行率存在困难,因为检测是在一小部分非随机人群中进行的。然而,住院患者的检测率非常高,即使是因非COVID原因入院的患者也是如此。我们展示了如何利用非COVID住院患者的检测信息,在比通常使用的条件更弱的条件下,获得人群流行率的紧致界限。我们将该方法应用于印第安纳州的检测和住院数据总体,并验证了我们的方法。我们的界限可以以相对较低的成本构建,且适用于其他接受大量检测的人群。

Abstract

Abstract Measuring the prevalence of active SARS-CoV-2 infections in the general population is difficult because tests are conducted on a small and nonrandom segment of the population. However, hospitalized patients are tested at very high rates, even those admitted for non-COVID reasons. We show how to use information on testing of non-COVID hospitalized patients to obtain tight bounds on population prevalence, under conditions weaker than those usually used. We apply our approach to the population of test and hospitalization data for Indiana, and we validate our approach. Our bounds could be constructed at relatively low cost, and for other heavily tested populations.
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