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诊断阈值、书面同意要求与稀缺器官的利用

Diagnostic Thresholds, Written Consent Requirements, and the Utilization of Scarce Organs
NBER Working Papers · 2026 · [{"name": "Hannah Bae", "affiliation": []}, {"name": "Jeffrey Clemens", "affiliation": []}]

中文摘要

本文探讨诊断阈值与书面同意要求如何影响患者与移植外科医生之间关于是否使用已故捐赠者肾脏的决策。基于覆盖美国全部器官捐赠者与移植受者的行政数据,我们发现,在2002年末至2014年末实施的扩展标准捐赠者系统(ECD)中,基于年龄的不连续性导致原本条件相同的肾脏被弃用的比率分别相差4.0个和5.4个百分点。随后引入的肾脏捐赠者概况指数(KDPI)中的一处不连续性则导致了2.6个百分点的差异。我们的证据表明,诊断阈值对决策与信息获取具有微妙的影响:例如,在ECD系统基于年龄的不连续点处,获取性活检(procurement biopsy)的比率显著上升。我们进一步表明,ECD与KDPI标签系统所触发的书面同意要求,大幅减少了在肾脏被弃用之前曾被提供给潜在受者的人数。这一渠道可以解释当前系统下"高KDPI"肾脏弃用率上升的大部分原因。

Abstract

This paper explores how diagnostic thresholds and a written consent requirement affect decision making between patients and transplant surgeons regarding the use of deceased donor kidneys. Combining administrative data on the universe of organ donors and transplant recipients in the United States, we show that age-based discontinuities within the Expanded Criteria Donor system (ECD), which was in place from late 2002 to late 2014, led to 4.0 and 5.4 percentage point differences in the rates at which otherwise indistinguishable kidneys were discarded. A discontinuity within the subsequent presentation of the Kidney Donor Profile Index (KDPI) led to a 2.6 percentage point difference. We present evidence that diagnostic thresholds have nuanced effects on decision making and information acquisition; procurement biopsy rates, for example, rose substantially at the ECD system’s age-based discontinuities. We further show that written consent requirements triggered within the ECD and KDPI labeling systems substantially reduced the number of potential recipients to whom kidneys were offered prior to being discarded. This channel can explain the majority of the increased rate at which “High-KDPI” kidneys are discarded under the current system.
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