社会经济健康差距的终身轨迹与驱动因素
Lifetime Trajectories and Drivers of Socioeconomic Health Disparities
Journal of Human Resources · 2025 · [{"name": "Ailun Shui", "affiliation": ["University of Groningen"]}, {"name": "Gerard J. van den Berg", "affiliation": ["University Medical Center Groningen"]}, {"name": "Jochen O. Mierau", "affiliation": ["University Medical Center Groningen"]}, {"name": "Laura Viluma", "affiliation": ["University of Groningen"]}]
中文摘要
我们利用荷兰 Lifelines 队列研究与生物样本库的纵向生物标志物，考察全生命周期中的社会经济健康差距。通过基于 12 项生物标志物构建适应负荷指数，我们分析了健康的动态变化及其在生命周期中与社会经济地位（SES）的关联。研究发现，与较低 SES 相关的健康风险在早期即已出现，并先于慢性疾病的发生。进一步分析考察了适应负荷的驱动因素，并强调了健康行为的作用。本研究凸显了针对 SES 相关健康差距开展早期干预的必要性，并为连接 SES 与长期健康结果的生理路径提供了新的见解。
Abstract
<h3>Abstract</h3> We investigate lifetime socioeconomic health disparities through longitudinal biomarkers from the Dutch Lifelines cohort study and biobank. By constructing an allostatic load index from 12 biomarkers, we analyze the dynamics of health and its association with socioeconomic status (SES) over the life cycle. Our findings reveal that health risks linked to lower SES emerge early and precede chronic disease onset. Further analyses investigate the drivers of allostatic load and emphasize health behaviors. Our research highlights the need for early interventions targeting SES-related health disparities and provides new insights into the physiological pathways linking SES to long-term health outcomes.